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Neuro Probe
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Neuro Probe
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Poretics Corporation
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Image Search Results
Journal: Frontiers in Immunology
Article Title: HMGB1-dependent signaling in the regulation of mast cell activity during inflammation
doi: 10.3389/fimmu.2025.1643427
Figure Lengend Snippet: Effect of HMGB1 on MC migratory response. MCs were incubated with HMGB1 at 0.1–10 ng/mL, TNF at 0.05 pg/mL (positive control; PC), or medium alone (spontaneous MC migration) in a Boyden microchamber. RAGE antagonist FPS-ZM1 was used at 5 μM before the MCs incubation with 10 ng/mL HMGB1. Spontaneous migration served as a control and was referred to as 100%. Results are expressed as a percentage of spontaneous migration. Each point represents the mean ± SD of three independent experiments, and each experiment was performed in duplicate. Differences were considered significant at P < 0.05 and are labelled with an asterisk (*) on each graph (Student’s t -test). P*** < 0.001.
Article Snippet: The MC migratory response to HMGB1 was investigated utilizing a
Techniques: Incubation, Positive Control, Migration, Control